Elite Clinic offers a DNA test prior to pregnancy which prevents genetic disorders in the baby.
The Carrier Screening Test or Carrier Genetic Test (CGT) is an important genetic test when planning a family, because it helps to determine the risk of having a child with a genetic disease. This test tells us whether the parents carry one or more known recessive genetic mutations. Carriers are usually healthy but when two parents carry a mutation in the same gene they might produce an affected child. Anyone, without knowing, can be a carrier of one or more mutations. The Carrier Screening Test allows us to know which genes are altered in each person.
The procedure is carried out through a simple blood analysis.
Link >> The list of genetic diseases tested
Why do a Carrier Screening Test?
Generally, parents only realize they are carriers of serious genetic disorders after an affected child is born. Genetic disorders can’t be cured, but they can be prevented. It is the only clinically validated test.
Who is the Carrier Screening Test for?
We all have changes in our genes and the carrier screening test allows us to find out whether they could cause a disease in our children.
The test is recommended in the following cases:
- Before attempting a pregnancy by natural means:
for any woman who wants to become pregnant in order to know the risk of transmitting possible disorders to her children. - Before an assisted reproduction treatment:
it is advisable to find out the risk of transmission and to be able to determine the best type of treatment in each case. - Before treatment with donor sperm or eggs:
In order to be able to select a donor that doesn’t carry the same mutation as the member of the couple who will provide the gametes (eggs or sperm).
Cost of test including CGT match (written information regarding risks and matching):
CGT Bank test – eligible for gamete donor testing, panel includes sequencing of 71 genes (7 autosomal + 64 X-linked genes), detects up to 75 genetic diseases igenomix: CGT Bank
575 EUR (donor) + 575 EUR (partner using donor) = 1150 EUR
CGTPlus test – suitable for patient research, panel includes sequencing of 519 genes (455 autosomal + 64 X-linked genes), detects up to 570 genetic diseases igenomix: CGT Plus
650 EUR (female partner) + 650 EUR (male partner) = 1300 EUR
CGTExome test – suitable for patient research, panel includes sequencing of 2276 genes (2084 autosomal + 192 X-linked genes), detects >2300 genetic diseases igenomix: CGT Exome
1000 EUR (female partner) + 1000 EUR (male partner) = 2000 EUR
The CGTPlus test and the CGT Exome test can also be used in donation programs.
Gynecologist consultation is added to the price.
Modern medicine has done much to offer more and more additional possibilities of genetic testing but they are rather expensive and do not give absolute information which kind of diseases will affect the future child, testing provides only the information about tested genes and their related diseases.
It helps to determine the risk of having a child with a genetic disease. This test tells us whether the parents carry one or more recessive genetic mutation. Carriers are usually healthy but when two parents carry a mutation in the same gene they might produce an affected child. Anyone, without knowing, can be a carrier of one or more mutations.
Most people today don’t use genetic matching and main reason for that is a high cost. At least you must know about this possibility.
Additional information:
- The test result takes up to 4 weeks. If you would like to perform the test, we can start with program after getting the result.
- Every man and every women has changes in their genes. If both a man and a woman have the same mutation the child might have a genetic disease. The result informes us about a risk, the results is not an absolute fact that a child will be affected. The global prevalence of all single gene diseases at birth is approximately 10/1000 : WHO-Genes and human diseases
- With the help of this test we can control only a part of the most common genetic diseases that occur more often, we cannot control and have information about all genetic diseases.
- According to scientific investigations maybe about 8% of donors are incompatible with your husband.
- All donors according to Estonian law are tested for karyotype, Cystic fibrosis and Fragile X chromosome. Our donors are investigated by a psychologist. This is a standard that is usually practised in IVF centres testing the donors in Europe.
- Each person has more than 100,000 genes. We do not test them, we don’t have enough knowledge about this complicated system.
Risk for genetics diseases is rather small but still exists as everyone has gene defects. And an additional testing could give additional information about the risks.